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"A ciência será sempre uma busca, jamais uma descoberta. É uma viagem, nunca uma chegada."

Karl Popper-

Publicações Acadêmicas Selecionadas

A three-sequence dynamic contrast enhanced abbreviated MRI protocol to evaluate response to breast cancer neoadjuvant chemotherapy. Magnetic Resonance Imaging, 2023.

 Evaluation of the antitumoral effects of the mesoionic compound MI-D: Implications for endothelial cells viability and angiogenesis inhibition. Chemico-Biological Interactions, 2023.

A remote, fully oriented personalized program of physical exercise for women in follow-up after breast cancer treatment improves body composition and physical fitness. Sports Medicine and Health Science, 2023.

 

Evidence that BJcuL, a C-type lectin from Bothrops jararacussu venom, influences deubiquitinase activity, resulting in the accumulation of anti-apoptotic proteins in two colorectal cancer cell lines. International Journal Of Biological Macromolecules, 2022

Systems biology network reveals the correlation between COX-2 expression and Ch 7q copy number alterations in Ch 11q-deleted pediatric neuroblastoma tumors. Genes and Cancer, 2022

 

Evidence that BJcuL, a C-type lectin from Bothrops jararacussu venom, influences deubiquitinase activity, resulting in the accumulation of anti-apoptotic proteins in two colorectal cancer cell lines. International Journal of Biological Macromolecules, 2022

 

 

An overview of neuroblastoma cell lineage phenotypes and models. Experimental Biology and Medicine, 2020.
 

 Crystallinity of TiO2 nanotubes and its effects on fibroblast viability, adhesion, and proliferation. Journal of Materials Science-Materials in Medicine, 2020.

Marine Actinomycetes-Derived Secondary Metabolites Overcome TRAIL-Resistance via the Intrinsic Pathway through Downregulation of Survivin and XIAP.  Cells, 2020.

 Neutrophils activated by BJcuL, a C-type lectin isolated from Bothrops jararacussu venom, decrease the invasion potential of neuroblastoma SK-N-SH cells in vitro. Journal of Venomous Animals and Toxins Including Tropical Diseases, 2020. 
 

Antiproliferative and antiangiogenic effect of Amblyomma sculptum (Acari: Ixodidae) crude saliva in

endothelial cells in vitro. Biomedicine & Pharmacotherapy, 2019. 

 

Antitumoral effects of Amblyomma sculptum Berlese saliva in neuroblastoma cell lines involve cytoskeletal deconstruction and cell cycle arrest. Revista Brasileira de Parasitologia Veterinária, 2019. 
 

Effect of crystalline phases of titania nanotube arrays on adipose derived stem cell adhesion and proliferation. Materials Science & Engineering C-Materials for Biological Applications, 2019. 

 

 Patterns of copy number alterations in primary breast tumors of South African patients and their impact on functional cellular pathways. International Journal of Oncology, 2018.
 

 

Cancer stem cell markers ALDH1 and CD44+/CD24- phenotype and their prognosis impact in invasive ductal carcinoma. European Journal of Histochemistry, 2018

 

Bjcul, A snake venom lectin, modulates monocyte-derived macrophages To A pro-Inflammatory profile In Vitro. Toxicology in Vitro, 2016. 


 BJcuL, a lectin purified from Bothrops jararacussu venom, induces apoptosis in human gastric carcinoma cells accompanied by inhibition of cell adhesion and actin cytoskeleton disassembly. Toxicon, 2012. 



 

Human neutrophil migration and activation by BJcuL, a galactose binding lectin purified from Bothrops jararacussu venom. BMC Immunology, 2011.

 


 

HER2-expressing breast tumors are associated with breast cancer stem-cell phenotype CD44+/CD24. Jornal Brasileiro de Patologia e Medicina Laboratorial, 2018

 


 

Death Receptor-Induced Apoptosis Signalling Regulation by Ezrin Is Cell Type Dependent and Occurs in a DISC-Independent Manner in Colon Cancer Cells. Plos One, 2015.


The lectin BJcuL induces apoptosis through TRAIL expression, caspase cascade activation and mitochondrial membrane permeability in a human colon adenocarcinoma cell line. Toxicon, 2014



Intradermal injection of Bothrops cotiara venom in mice in an experimental wound model.  Journal of Venomous Animals and Toxins including Tropical Diseases, 2012
 

A C-type lectin from Bothrops jararacussu venom can adhere to extracellular matrix proteins and induce the rolling of leukocytes. Journal of Venomous Animals and Toxins including Tropical Diseases 2007.

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